Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 3/20 | 0.57 |
| ▸ | GSK3B | P49841 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5457409 | 0.80 | GSK3A (0.81) | GSK3AGSK3BPOLBALDH1A1HDAC1 | |
| SCHEMBL5427372 | 0.77 | GSK3A (0.54) | GSK3AGSK3BPOLBALDH1A1HDAC1 | |
| SCHEMBL7252535 | 0.76 | GSK3A (0.82) | GSK3AGSK3BPOLBALDH1A1HDAC1 | |
| SCHEMBL338442 | 0.74 | GSK3A (1.00) | GSK3AGSK3BPOLBALDH1A1HDAC1 | |
| SCHEMBL7462946 | 0.72 | GSK3A (0.67) | GSK3AGSK3BPOLBALDH1A1HDAC1 | |
| SCHEMBL5455104 | 0.72 | GSK3A (0.71) | GSK3AGSK3BPOLBALDH1A1HDAC1 | |
| SCHEMBL7460972 | 0.72 | GSK3A (0.67) | GSK3AGSK3BPOLBALDH1A1HDAC1 | |
| SCHEMBL6692164 | 0.72 | GSK3A (0.70) | GSK3AGSK3BPOLBALDH1A1HDAC1 | |
| SCHEMBL6992265 | 0.71 | GSK3A (0.79) | GSK3AGSK3BPOLBALDH1A1HDAC1 | |
| SCHEMBL5454906 | 0.70 | GSK3A (0.72) | GSK3AGSK3BPOLBALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309575-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | Galderma Research & Development (FR) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | disclosed |
| WO-2002012210-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-02-14 | — | — | WO | disclosed |