Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.61 |
| ▸ | CA2 | P00918 | 8/20 | 0.61 |
| ▸ | CA12 | O43570 | 5/20 | 0.61 |
| ▸ | CA7 | P43166 | 3/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.61 |
| ▸ | PNMT | P11086 | 6/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30688582 | 1.00 | CA1 (0.61) | CA1CA2CA12CA7CA14 | |
| SCHEMBL30688580 | 0.93 | CA1 (0.61) | CA1CA2CA12CA7CA14 | |
| SCHEMBL6121352 | 0.85 | CA2 (0.63) | CA1CA2CA12CA7CA14 | |
| SCHEMBL7089572 | 0.79 | HTR2C (0.59) | HTR6HTR2C | |
| SCHEMBL29273178 | 0.76 | HTR2C (0.42) | CA1CA2CA12CA7CA14 | |
| SCHEMBL25236396 | 0.76 | HTR6 (0.46) | CA1CA2CA12CA7CA14 | |
| SCHEMBL8879406 | 0.76 | CA1 (0.92) | CA1CA2CA12CA7CA14 | |
| SCHEMBL29519756 | 0.76 | CA1 (1.00) | CA1CA2CA12CA7CA14 | |
| SCHEMBL2011443 | 0.76 | CA1 (1.00) | CA1CA2CA12CA7CA14 | |
| SCHEMBL23555203 | 0.74 | PKM (0.65) | CA1CA2CA12CA9HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345930-A2 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050067-A2 | PHARMACEUTICAL HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 2002-06-27 | — | — | WO | disclosed |