⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1078901 | 0.77 | — | — | |
| SCHEMBL1594976 | 0.75 | — | — | |
| SCHEMBL28022191 | 0.70 | — | — | |
| SCHEMBL28477002 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL7106585 | 0.69 | — | — | |
| SCHEMBL2221057 | 0.69 | — | — | |
| SCHEMBL534 | 0.67 | — | — | |
| SCHEMBL9803758 | 0.67 | — | — | |
| SCHEMBL592248 | 0.67 | — | — | |
| SCHEMBL4683308 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814324-A1 | CATHEPSIN C INHIBITORS | National Institute Of Biological Sciences, Beijing (CN) | 2021-05-05 | — | — | EP | disclosed |
| CN-106905357-B | Preparation method of silthiopham key intermediate | 南京工业大学 | 2019-04-09 | — | — | CN | disclosed |
| CN-106905357-A | Preparation method of silthiopham key intermediate | 南京工业大学 | 2017-06-30 | — | — | CN | disclosed |
| US-8298622-B2 | Silica aerogel coating and its production method | Pentax Ricoh Imaging Company, Ltd. (JP) | 2012-10-30 | — | — | US | disclosed |
| US-8199404-B2 | Anti-reflection coating, optical member, exchange lens unit and imaging device | Pentax Ricoh Imaging Company, Ltd. (JP) | 2012-06-12 | — | — | US | disclosed |
| US-8125714-B2 | Anti-reflection coating, optical member, exchange lens unit and imaging device | Pentax Ricoh Imaging Company, Ltd. (JP) | 2012-02-28 | — | — | US | disclosed |
| US-8029871-B2 | Method for producing silica aerogel coating | HOYA CORPORATION (JP) | 2011-10-04 | — | — | US | disclosed |
| EP-1692116-B1 | 1,2,3-TRIAZOLE AMIDE DERIVATIVES AS INHIBITORS OF CYTOKINE PRODUCTION | BOEHRINGER INGELHEIM PHARMA (US) | 2011-03-09 | — | — | EP | disclosed |
| US-20090219620-A1 | ANTI-REFLECTION COATING, OPTICAL MEMBER, EXCHANGE LENS UNIT AND IMAGING DEVICE | HOYA CORPORATION (JP) | 2009-09-03 | — | — | US | disclosed |
| US-20090168184-A1 | ANTI-REFLECTION COATING, OPTICAL MEMBER, EXCHANGE LENS UNIT AND IMAGING DEVICE | HOYA CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |
| US-7531560-B2 | Anti-cytokine heterocyclic compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-05-12 | — | — | US | disclosed |
| US-7511042-B2 | 1-[5-(5-tert-Butyl-2-methoxy-3-methylsulfamoyl-phenylcarbamoyl)-2-methyl-phenyl]-1H-1,2,3-triazole-4-carboxylic acid (2,2-dimethyl-propyl)-amide; small molecule cytokine inhibitor; optimized efficacy, pharmacokinetic; antiinflammatory agent, osteoarthritis, asthma, gastrointestinal, respiratory disorder | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-7511042-B2 | 1-[5-(5-tert-Butyl-2-methoxy-3-methylsulfamoyl-phenylcarbamoyl)-2-methyl-phenyl]-1H-1,2,3-triazole-4-carboxylic acid (2,2-dimethyl-propyl)-amide; small molecule cytokine inhibitor; optimized efficacy, pharmacokinetic; antiinflammatory agent, osteoarthritis, asthma, gastrointestinal, respiratory disorder | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-20060281828-A1 | METHOD FOR PRODUCING SILICA AEROGEL COATING | PENTAX CORPORATION (JP) | 2006-12-14 | — | — | US | disclosed |
| US-20060239886-A1 | Silica aerogel coating and its production method | PENTAX CORPORATION (JP) | 2006-10-26 | — | — | US | disclosed |
| EP-1692116-A1 | 1,2,3-TRIAZOLE AMIDE DERIVATIVES AS INHIBITORS OF CYTOKINE PRODUCTION | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2006-08-23 | — | — | EP | disclosed |
| US-20060100204-A1 | Heterocyclic-substituted benzamide derivatives, e.g., benzyl [2-(4-{1-[5-(5-tert-Butyl-3-methanesulfonylamino-2-methoxy-phenylcarbamoyl)-2-methyl-phenyl]-1H-1,2,3-triazol-4-yl}-2-phenyl-2H-pyrazol-3-yl)-ethyl]-carbamate; inhibit production of cytokines; useful for treating chronic inflammatory disease. | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-05-11 | — | — | US | disclosed |
| US-20050153972-A1 | 1-[5-(5-tert-Butyl-2-methoxy-3-methylsulfamoyl-phenylcarbamoyl)-2-methyl-phenyl]-1H-1,2,3-triazole-4-carboxylic acid (2,2-dimethyl-propyl)-amide; small molecule cytokine inhibitor; optimized efficacy, pharmacokinetic; antiinflammatory agent, osteoarthritis, asthma, gastrointestinal, respiratory disorder | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-07-14 | — | — | US | disclosed |
| WO-2005056535-A1 | 1,2,3-TRIAZOLE AMIDE DERIVATIVES AS INHIBITORS OF CYTOKINE PRODUCTION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-06-23 | — | — | WO | disclosed |
| US-6013413-A | Alicyclic nortricyclene polymers and co-polymers | CORNELL RESEARCH FOUNDATION, INC. (US) | 2000-01-11 | — | — | US | disclosed |