Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | TLR3 | O15455 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4846177 | 1.00 | HTT (0.39) | HTTMAPTSMN1; SMN2LMNAAKR1B1 | |
| SCHEMBL4873736 | 1.00 | HTT (0.39) | HTTMAPTSMN1; SMN2LMNAAKR1B1 | |
| SCHEMBL4873739 | 1.00 | HTT (0.39) | HTTMAPTSMN1; SMN2LMNAAKR1B1 | |
| SCHEMBL8536317 | 0.88 | MAPT (0.39) | HTTMAPTSMN1; SMN2LMNAAKR1B1 | |
| SCHEMBL8536503 | 0.88 | MAPT (0.39) | HTTMAPTSMN1; SMN2LMNAAKR1B1 | |
| SCHEMBL9767087 | 0.86 | AKR1B1 (0.39) | HTTMAPTSMN1; SMN2LMNAAKR1B1 | |
| SCHEMBL6985760 | 0.85 | AKR1B1 (0.40) | HTTMAPTSMN1; SMN2LMNAAKR1B1 | |
| SCHEMBL2475336 | 0.81 | AKR1B1 (0.37) | HTTMAPTSMN1; SMN2LMNAAKR1B1 | |
| SCHEMBL7965091 | 0.81 | TLR3 (0.40) | HTTMAPTSMN1; SMN2LMNAAKR1B1 | |
| SCHEMBL6985601 | 0.81 | AKR1B1 (0.37) | HTTMAPTSMN1; SMN2LMNAAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1229371-C | Benzopyran guanidine derivatives, process for preparing the same, and pharmaceutical composition thereof | KOREA RES INST CHEM TECH (KR) | 2005-11-30 | — | — | CN | disclosed |
| EP-1228058-B1 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2003-12-10 | — | — | EP | disclosed |
| CN-1382134-A | Benzopyranyl guanidine derivtives, process for preparation thereof and pharmaceutical compositions containing them | KOREA RES INST CHEM TECH (KR) | 2002-11-27 | — | — | CN | disclosed |
| US-6323238-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2001-11-27 | — | — | US | disclosed |