Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TLR3 | O15455 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536317 | 1.00 | MAPT (0.39) | MAPTHTTLMNASMN1; SMN2TLR3 | |
| SCHEMBL4846177 | 0.88 | HTT (0.39) | MAPTHTTLMNASMN1; SMN2TLR3 | |
| SCHEMBL4873736 | 0.88 | HTT (0.39) | MAPTHTTLMNASMN1; SMN2TLR3 | |
| SCHEMBL6987633 | 0.88 | HTT (0.39) | MAPTHTTLMNASMN1; SMN2TLR3 | |
| SCHEMBL4873739 | 0.88 | HTT (0.39) | MAPTHTTLMNASMN1; SMN2TLR3 | |
| SCHEMBL9766984 | 0.86 | LMNA (0.37) | MAPTHTTLMNASMN1; SMN2TLR3 | |
| SCHEMBL8130434 | 0.84 | LMNA (0.35) | MAPTHTTLMNASMN1; SMN2TLR3 | |
| SCHEMBL9767647 | 0.82 | ESPL1 (0.43) | MAPTHTTLMNASMN1; SMN2TLR3 | |
| SCHEMBL2471965 | 0.81 | AKR1B1 (0.37) | MAPTHTTLMNASMN1; SMN2TLR3 | |
| SCHEMBL6985601 | 0.81 | AKR1B1 (0.37) | MAPTHTTLMNASMN1; SMN2TLR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719155-A | CARDIOVASCULAR DISORDERS | JAPAN TOBACCO INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | disclosed |