Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR3 | O15455 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767130 | 0.88 | AKR1B1 (0.40) | TLR3AKR1B1HTTMAPTSMN1; SMN2 | |
| SCHEMBL9767136 | 0.88 | AKR1B1 (0.40) | TLR3AKR1B1HTTMAPTSMN1; SMN2 | |
| SCHEMBL7961450 | 0.88 | AKR1B1 (0.40) | TLR3AKR1B1HTTMAPTSMN1; SMN2 | |
| SCHEMBL9767134 | 0.88 | AKR1B1 (0.40) | TLR3AKR1B1HTTMAPTSMN1; SMN2 | |
| SCHEMBL9195046 | 0.82 | ABCC9 (0.44) | TLR3AKR1B1HTTMAPTSMN1; SMN2 | |
| SCHEMBL9195025 | 0.82 | ABCC9 (0.44) | TLR3AKR1B1HTTMAPTSMN1; SMN2 | |
| SCHEMBL9195034 | 0.82 | ABCC9 (0.44) | TLR3AKR1B1HTTMAPTSMN1; SMN2 | |
| SCHEMBL8310989 | 0.81 | HTT (0.40) | TLR3AKR1B1HTTMAPTSMN1; SMN2 | |
| SCHEMBL6987633 | 0.81 | HTT (0.39) | TLR3AKR1B1HTTMAPTSMN1; SMN2 | |
| SCHEMBL4873739 | 0.81 | HTT (0.39) | TLR3AKR1B1HTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323238-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2001-11-27 | — | — | US | disclosed |