Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987035 | 0.87 | ROCK2 (0.40) | HTR4KMT2ASMN1; SMN2NPC1LMNA | |
| SCHEMBL6989025 | 0.87 | HTR4 (0.43) | HTR4KDM1AEP300KMT2ASMN1; SMN2 | |
| SCHEMBL6985733 | 0.87 | HTR4 (0.43) | HTR4KDM1AEP300KMT2ASMN1; SMN2 | |
| SCHEMBL6990414 | 0.87 | HTR4 (0.43) | HTR4KDM1AEP300KMT2ASMN1; SMN2 | |
| SCHEMBL6986612 | 0.86 | HTR4 (0.43) | HTR4KDM1AEP300KMT2ASMN1; SMN2 | |
| SCHEMBL6985413 | 0.86 | HTR4 (0.43) | HTR4KDM1AEP300KMT2ASMN1; SMN2 | |
| SCHEMBL6983529 | 0.84 | HTR4 (0.42) | HTR4KDM1AEP300KMT2ASMN1; SMN2 | |
| SCHEMBL6987917 | 0.84 | HTR4 (0.42) | HTR4KDM1AEP300KMT2ASMN1; SMN2 | |
| SCHEMBL6990268 | 0.83 | HTR4 (0.41) | HTR4KDM1AEP300KMT2ASMN1; SMN2 | |
| SCHEMBL6989855 | 0.81 | BRD4 (0.47) | HTR4KDM1AEP300KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289954-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096303-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |