Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986315 | 0.75 | SMN1; SMN2 (0.64) | NPSR1POLBHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL6777058 | 0.64 | POLB (0.47) | NPSR1POLBHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL18865500 | 0.58 | ALKBH5 (0.50) | NPSR1POLBHPGDHSD17B10FAAH | |
| SCHEMBL636960 | 0.58 | VHL (0.50) | NPSR1POLBHPGDSMN1; SMN2FAAH | |
| SCHEMBL8507769 | 0.58 | CYP2A6 (0.44) | NPSR1FAAHMGLLHTTCYP2A6 | |
| SCHEMBL18508 | 0.58 | — | — | |
| SCHEMBL17304833 | 0.55 | CYP2A6 (0.40) | NPSR1POLBHPGDHSD17B10FAAH | |
| SCHEMBL31252540 | 0.55 | AKR1C3 (0.57) | HTTCYP2A6ALDH1A1KMT2A | |
| SCHEMBL15987789 | 0.55 | CYP2A6 (0.47) | POLBHSD17B10FAAHMGLLCYP2A6 | |
| SCHEMBL3138002 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030125325-A1 | Pyrazolyl benzyl thioethers | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-03 | — | — | US | disclosed |
| EP-1273573-A1 | Pyrazolylbenzylthioethers and their use for combating organisms which are harmful to plants | Bayer CropScience AG (DE) | 2003-01-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125325-A1 | Pyrazolyl benzyl thioethers | TST, TPMT, PTBP3 | NPSR1 4358/4885POLB 3024/4885HPGD 2441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.