Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984938 | 0.79 | L3MBTL1 (0.36) | L3MBTL1TDP1LMNASMN1; SMN2MAOA | |
| SCHEMBL9229707 | 0.78 | TDP1 (0.34) | L3MBTL1TDP1LMNASMN1; SMN2MAPT | |
| SCHEMBL15912538 | 0.74 | KDM4E (0.41) | L3MBTL1LMNASMN1; SMN2MAPTMAOA | |
| SCHEMBL5081592 | 0.74 | LMNA (0.40) | L3MBTL1LMNASMN1; SMN2MAPTMAOA | |
| SCHEMBL95522 | 0.73 | LMNA (0.42) | L3MBTL1LMNASMN1; SMN2MAPTMAOA | |
| SCHEMBL16329923 | 0.73 | LMNA (0.34) | KMT2AL3MBTL1LMNASMN1; SMN2MAOA | |
| SCHEMBL6988675 | 0.71 | SLC1A3 (0.45) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL23414339 | 0.71 | LMNA (0.38) | L3MBTL1LMNASMN1; SMN2MAPTMAOA | |
| SCHEMBL4594959 | 0.71 | SMN1; SMN2 (0.43) | L3MBTL1LMNASMN1; SMN2MAPTMAOA | |
| SCHEMBL21253055 | 0.69 | LMNA (0.44) | KMT2AL3MBTL1TDP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318978-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | Abbott Laboratories (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024636-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2002-03-28 | — | — | WO | disclosed |