Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6706266 | 0.75 | KMT2A (0.47) | KMT2AMEN1MAPTHPGDTDP1 | |
| SCHEMBL5999001 | 0.73 | NQO2 (0.62) | KMT2AMEN1MAPTHPGDATM | |
| SCHEMBL1709278 | 0.73 | MEN1 (0.57) | KMT2AMEN1MAPTHPGDATM | |
| SCHEMBL14108276 | 0.71 | OPRD1 (0.55) | KMT2AMEN1MAPTHPGDATM | |
| SCHEMBL14108273 | 0.71 | MEN1 (0.55) | KMT2AMEN1MAPTHPGDATM | |
| SCHEMBL12250922 | 0.71 | ATM (0.57) | KMT2AMEN1MAPTHPGDATM | |
| SCHEMBL22651839 | 0.70 | CYP1A2 (0.59) | KMT2AMEN1MAPTATMTDP1 | |
| SCHEMBL5697805 | 0.70 | MEN1 (0.57) | KMT2AMEN1MAPTHPGDATM | |
| SCHEMBL22323341 | 0.70 | MEN1 (0.66) | KMT2AMEN1MAPTTDP1CA2 | |
| SCHEMBL6989120 | 0.70 | CA2 (0.50) | KMT2AMEN1MAPTHPGDCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1332127-A2 | AMIDINO-UREA SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SNYTHESIS | Warner-Lambert Company LLC (US) | 2003-08-06 | — | — | EP | disclosed |
| WO-2002036554-A2 | AMIDINO-UREA SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SNYTHESIS | WARNER-LAMBERT COMPANY LLC (US) | 2002-05-10 | — | — | WO | disclosed |