Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754346 | 0.88 | L3MBTL1 (0.56) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL4344803 | 0.88 | L3MBTL1 (0.58) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL16772764 | 0.87 | L3MBTL1 (0.57) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL25801927 | 0.84 | L3MBTL1 (0.63) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL16993182 | 0.83 | L3MBTL1 (0.62) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL25250171 | 0.83 | L3MBTL1 (0.61) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL2286496 | 0.82 | L3MBTL1 (0.47) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6400630 | 0.82 | L3MBTL1 (0.47) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL8501723 | 0.81 | L3MBTL1 (0.59) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL4344800 | 0.81 | L3MBTL1 (0.59) | L3MBTL1PPARACTSBNPSR1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318978-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | Abbott Laboratories (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024636-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2002-03-28 | — | — | WO | disclosed |