SCHEMBL69880

SCHEMBL69880

O=C(O)c1ccc(Cl)c(C(=O)O)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.68
ALDH1A1 P00352 3/20 0.65
TP53 P04637 2/20 0.65
KDM4E B2RXH2 4/20 0.55
TDP1 Q9NUW8 4/20 0.55
MAPT P10636 3/20 0.55
POLB P06746 3/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
SRD5A2 P31213 2/20 0.53
LMNA P02545 1/20 0.53
ALOX15 P16050 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
CTSB P07858 1/20 0.50
CASP1 P29466 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9618407 0.98 TSHR (0.65) TSHRALDH1A1TP53KDM4ETDP1
Isophthalic Acid SCHEMBL11351490 0.92 TSHR (0.59) TSHRALDH1A1TP53KDM4ETDP1
SCHEMBL14421296 0.89 ALDH1A1 (0.63) TSHRALDH1A1TP53KDM4ETDP1
SCHEMBL7015121 0.85 TSHR (0.61) TSHRALDH1A1TP53KDM4ETDP1
SCHEMBL9721168 0.83 CDC25B (0.61) TSHRALDH1A1TP53KDM4EPOLB
SCHEMBL18398078 0.82 ALDH1A1 (0.55) TSHRALDH1A1TP53KDM4ETDP1
SCHEMBL14421333 0.82 ALDH1A1 (0.66) TSHRALDH1A1TP53KDM4ETDP1
SCHEMBL30162746 0.82 TSHR (0.68) TSHRALDH1A1TP53KDM4EMAPT
SCHEMBL68294 0.82 TSHR (0.68) TSHRALDH1A1TP53KDM4EMAPT
SCHEMBL29353637 0.81 TSHR (1.00) TSHRALDH1A1KDM4EMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114016285-B Preparation method of functional nanofiber membrane for sea water desalination 盐城工业职业技术学院 2024-01-30 CN claimed
CN-116554491-A Method for breaking pH limit of nano enzyme to degrade phenol pollutants in water 天津工业大学 2023-08-08 CN claimed
CN-113893707-B C (C) 1 -C 4 Mixed matrix membrane with preferential permeation of hydrocarbon, preparation method and application thereof 天津工业大学 2023-06-23 CN claimed
CN-116173749-A Preparation method of high-performance porous coordination polymer membrane 天津工业大学 2023-05-30 CN claimed
CN-114016285-A Preparation method of functional nanofiber membrane for seawater desalination 盐城工业职业技术学院 2022-02-08 CN claimed
CN-113893707-A C1-C4Mixed matrix membrane with preferential permeation of hydrocarbon, preparation method and application thereof 天津工业大学 2022-01-07 CN claimed
CN-113796385-A Silver ion-containing chlorhexidine salt compound and preparation method and application thereof 洛阳冠银生物科技有限公司 2021-12-17 CN claimed
CN-113667137-A Preparation method and application of two-dimensional metal-organic framework material 天津工业大学 2021-11-19 CN claimed
US-20100056750-A1 PROCESS FOR THE SYNTHESIS OF HALOGENATED AROMATIC DIACIDS E. I. DU PONT DE NEMOURS AND COMPANY 2010-03-04 US claimed
EP-2111388-A1 PROCESS FOR THE SYNTHESIS OF HALOGENATED AROMATIC DIACIDS E. I. Du Pont de Nemours and Company (US) 2009-10-28 EP claimed
WO-2008082501-A1 PROCESS FOR THE SYNTHESIS OF HALOGENATED AROMATIC DIACIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-10 WO claimed
US-4042571-A Fire-retardant polyamides from naphthalene dicarboxylic reactant and halogenated carboxylic reactant TEIJIN LIMITED (JA) 1977-08-16 US claimed
CN-118909266-A PLA active air-adjusting fruit and vegetable fresh-keeping bag 普思微(上海)生物材料有限公司 2024-11-08 CN disclosed
CN-117776858-A Preparation method of 2, 4-bistrifluoromethyl chlorobenzene 福建康峰新材料有限公司 2024-03-29 CN disclosed
CN-114755316-B Method for screening dangerous substances in food contact material and application 广州质量监督检测研究院 2024-02-27 CN disclosed
CN-114016285-B Preparation method of functional nanofiber membrane for sea water desalination 盐城工业职业技术学院 2024-01-30 CN disclosed
US-3959310-A BENZINDOLE BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed
US-3956264-A Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed
US-3950347-A NAPHTHOLACTAM DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-13 US disclosed
US-3948877-A POLYACRYLONITRILE, ACID MODIFIED POLYESTERS OR POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100056750-A1 PROCESS FOR THE SYNTHESIS OF HALOGENATED AROMATIC DIACIDS TYR, DDC, DDT TSHR 2744/4885ALDH1A1 1407/4885TP53 1176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.