Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988076 | 0.87 | MCL1 (0.58) | MTNR1AMTNR1BNOD2NOD1KMT2A | |
| SCHEMBL18537881 | 0.87 | NR1H2 (0.53) | MTNR1AMTNR1B | |
| SCHEMBL4794627 | 0.83 | MTNR1A (0.57) | MTNR1AMTNR1BNOD2NOD1KMT2A | |
| SCHEMBL7873282 | 0.82 | MTNR1A (0.56) | MTNR1AMTNR1BNOD2NOD1KMT2A | |
| SCHEMBL7884242 | 0.80 | DAO (0.64) | MTNR1AMTNR1BNOD2NOD1KMT2A | |
| SCHEMBL29834903 | 0.80 | L3MBTL1 (0.67) | MTNR1AMTNR1BKMT2AMCL1L3MBTL1 | |
| SCHEMBL4486403 | 0.80 | L3MBTL1 (0.67) | MTNR1AMTNR1BKMT2AMCL1L3MBTL1 | |
| SCHEMBL4740170 | 0.80 | MTNR1A (0.53) | MTNR1AMTNR1BNOD2NOD1KMT2A | |
| SCHEMBL1672526 | 0.80 | MTNR1A (0.48) | MTNR1AMTNR1BNOD2NOD1KMT2A | |
| SCHEMBL17075022 | 0.79 | L3MBTL1 (0.47) | MTNR1AMTNR1BNOD2NOD1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335917-A2 | CONDENSED PYRIDOINDOLE DERIVATIVES | Lilly Icos LLC (US) | 2003-08-20 | — | — | EP | claimed |
| WO-2002028859-A2 | CONDENSED PYRIDOINDOLE DERIVATIVES | LILLY ICOS LLC (US) | 2002-04-11 | — | — | WO | claimed |