Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002686 | 0.89 | ALDH1A1 (0.39) | TSHRALDH1A1LMNACYP2C19HTT | |
| SCHEMBL6003862 | 0.83 | TSHR (0.53) | TSHRALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL4805775 | 0.82 | ALDH1A1 (0.55) | TSHRALDH1A1LMNACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL6757406 | 0.82 | TSHR (0.51) | TSHRALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL4802151 | 0.74 | TSHR (0.50) | TSHRALDH1A1LMNAPOLBADORA2A | |
| SCHEMBL1801928 | 0.73 | MEN1 (0.59) | TSHRALDH1A1POLBADORA2AADORA1 | |
| SCHEMBL145302 | 0.73 | NPC1 (0.57) | TSHRALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL144813 | 0.72 | TSHR (0.69) | TSHRALDH1A1CYP2C19POLBADORA2A | |
| SCHEMBL6002694 | 0.70 | TSHR (0.47) | TSHRALDH1A1NPSR1POLBADORA2A | |
| SCHEMBL4805719 | 0.70 | TSHR (0.53) | TSHRALDH1A1HTTNPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1236460-B1 | Bridged diamino pyrazoles and colouring agents containing them | WELLA AG (DE) | 2003-11-26 | — | — | EP | claimed |