Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988147 | 0.89 | TSHR (0.46) | ALDH1A1LMNAMAPTTSHRNPC1 | |
| SCHEMBL6003395 | 0.72 | P2RX3 (0.35) | ALDH1A1MAPTGAATSHRSMN1; SMN2 | |
| SCHEMBL4805719 | 0.72 | TSHR (0.53) | ALDH1A1MAPTTSHRNPC1NPSR1 | |
| SCHEMBL6002675 | 0.72 | TSHR (0.36) | ALDH1A1LMNAMAPTGAAKDM4E | |
| SCHEMBL6002694 | 0.72 | TSHR (0.47) | ALDH1A1MAPTGAATSHRRECQL | |
| SCHEMBL145302 | 0.71 | NPC1 (0.57) | ALDH1A1LMNAMAPTGAATSHR | |
| SCHEMBL6003921 | 0.70 | TSHR (0.42) | ALDH1A1LMNATSHRRECQLNPSR1 | |
| SCHEMBL4805775 | 0.70 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTTSHRNPSR1 | |
| SCHEMBL6242716 | 0.68 | TSHR (0.44) | ALDH1A1MAPTGAATSHRNPSR1 | |
| Sulfuric Acid SCHEMBL2912572 | 0.68 | NPC1 (0.56) | ALDH1A1LMNAMAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257249-B1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AG (DE) | 2006-11-02 | — | — | EP | claimed |
| US-7018426-B2 | Oxidation dye | WELLA AG (DE) | 2006-03-28 | — | — | US | claimed |
| WO-2005023209-A1 | AGENT AND METHOD FOR DYEING KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2005-03-17 | — | — | WO | claimed |
| EP-1313434-B1 | OXIDATION DYE | WELLA AG (DE) | 2005-01-12 | — | — | EP | claimed |
| US-6793687-B2 | YELLOW AND ORANGE RANGE COLORING | WELLA AKTIENGESELLSCHAFT (DE) | 2004-09-21 | — | — | US | claimed |
| US-6716257-B2 | OXIDATION DYES, WHICH ARE USED FOR TREATMENT OF HUMAN HAIR | WELLA AKTIENGESELLSCHAFT (DE) | 2004-04-06 | — | — | US | claimed |
| EP-1236460-B1 | Bridged diamino pyrazoles and colouring agents containing them | WELLA AG (DE) | 2003-11-26 | — | — | EP | claimed |
| US-20030159222-A1 | Oxidation dye | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-08-28 | — | — | US | claimed |
| US-20030131423-A1 | Diaminopyrazole derivatives and oxidation hair dye containing pyrazolone derivatives | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-17 | — | — | US | claimed |
| EP-1313434-A1 | OXIDATION DYE | Wella Aktiengesellschaft (DE) | 2003-05-28 | — | — | EP | claimed |
| US-20020170125-A1 | Bridged diaminopyrazole compounds and dye compositions containing same | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2002-11-21 | — | — | US | claimed |
| EP-1257249-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2002-11-20 | — | — | EP | claimed |
| WO-2002069919-A1 | OXIDATION DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | claimed |
| WO-2002069918-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | claimed |
| EP-1236460-A1 | Bridged diamino pyrazoles and colouring agents containing them | Wella Aktiengesellschaft (DE) | 2002-09-04 | — | — | EP | claimed |
| EP-1257249-B1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AG (DE) | 2006-11-02 | — | — | EP | disclosed |
| US-7018426-B2 | Oxidation dye | WELLA AG (DE) | 2006-03-28 | — | — | US | disclosed |
| EP-1257249-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2002-11-20 | — | — | EP | disclosed |
| WO-2002069918-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |
| WO-2002069919-A1 | OXIDATION DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030159222-A1 | Oxidation dye | KRT18, NOX4, VIM | ALDH1A1 55/4885LMNA 924/4885MAPT 616/4885 |
| US-20030131423-A1 | Diaminopyrazole derivatives and oxidation hair dye containing pyrazolone derivatives | KRT18, AOC1, PPOX | ALDH1A1 70/4885LMNA 3025/4885MAPT 1130/4885 |
| US-20020170125-A1 | Bridged diaminopyrazole compounds and dye compositions containing same | ALK, DDC, CBR1 | ALDH1A1 11/4885LMNA 699/4885MAPT 4236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.