Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685035 | 0.76 | L3MBTL1 (0.48) | SLC6A2MAOBL3MBTL1POLBMEN1 | |
| SCHEMBL8910211 | 0.76 | SLC6A2 (0.45) | SLC6A2TAAR1MAOBLMNACYP2D6 | |
| SCHEMBL11047843 | 0.74 | L3MBTL1 (0.47) | SLC6A2MAOBL3MBTL1POLBMEN1 | |
| SCHEMBL3804525 | 0.72 | POLB (0.49) | SLC6A2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL28882516 | 0.72 | FAAH (0.46) | SLC6A2MAOBL3MBTL1POLBMEN1 | |
| SCHEMBL28737092 | 0.72 | L3MBTL1 (0.45) | SLC6A2MAOBL3MBTL1POLBMEN1 | |
| SCHEMBL3797223 | 0.72 | TAAR1 (0.56) | SLC6A2TAAR1MAOBL3MBTL1MEN1 | |
| SCHEMBL8851534 | 0.72 | L3MBTL1 (0.45) | SLC6A2MAOBL3MBTL1POLBMEN1 | |
| SCHEMBL11855325 | 0.71 | POLB (0.41) | L3MBTL1POLBMEN1KMT2ASIGMAR1 | |
| Bromide SCHEMBL11133528 | 0.71 | SLC6A2 (0.54) | SLC6A2TAAR1MAOBL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294695-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-03-26 | — | — | EP | claimed |
| WO-2001085694-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-11-15 | — | — | WO | claimed |