Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | FPR2 | P25090 | 16/20 | 0.41 |
| ▸ | FPR1 | P21462 | 12/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990577 | 0.88 | ALDH1A1 (0.44) | F10FPR2FPR1 | |
| SCHEMBL6988777 | 0.87 | F10 (0.46) | F10FPR2FPR1 | |
| SCHEMBL7091549 | 0.86 | F10 (0.44) | F10FPR2FPR1 | |
| SCHEMBL7090736 | 0.81 | F10 (0.43) | F10FPR2FPR1 | |
| SCHEMBL4680127 | 0.81 | F10 (0.57) | F10FPR2FPR1 | |
| SCHEMBL6985111 | 0.78 | F10 (0.49) | F10FPR2FPR1 | |
| SCHEMBL6986053 | 0.76 | F10 (0.35) | F10FPR2FPR1 | |
| SCHEMBL6981073 | 0.74 | F10 (0.56) | F10FPR2FPR1 | |
| SCHEMBL7090057 | 0.74 | F10 (0.46) | F10FPR2FPR1 | |
| SCHEMBL6987862 | 0.73 | F10 (0.54) | F10FPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337251-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2003-08-27 | — | — | EP | claimed |
| WO-2002102380-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-12-27 | — | — | WO | claimed |
| EP-1337251-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002102380-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-12-27 | — | — | WO | disclosed |