Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 12/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 7/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683589 | 0.83 | F10 (0.55) | F10FPR2FPR1 | |
| SCHEMBL6988777 | 0.82 | F10 (0.46) | F10FPR2FPR1 | |
| SCHEMBL7091549 | 0.82 | F10 (0.44) | F10FPR2FPR1 | |
| SCHEMBL6988428 | 0.81 | F10 (0.44) | F10FPR2FPR1 | |
| SCHEMBL6990577 | 0.80 | ALDH1A1 (0.44) | F10FPR2FPR1 | |
| SCHEMBL6986053 | 0.73 | F10 (0.35) | F10FPR2FPR1 | |
| SCHEMBL6981073 | 0.72 | F10 (0.56) | F10FPR2FPR1 | |
| SCHEMBL4684711 | 0.71 | F10 (0.54) | F10FPR2FPR1 | |
| SCHEMBL6987862 | 0.70 | F10 (0.54) | F10FPR2FPR1 | |
| SCHEMBL6985267 | 0.70 | FPR2 (0.55) | F10FPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337251-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2003-08-27 | — | — | EP | claimed |
| WO-2002102380-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-12-27 | — | — | WO | claimed |
| EP-1337251-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002102380-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-12-27 | — | — | WO | disclosed |