SCHEMBL698855

SCHEMBL698855

CS(=O)(=O)Nc1cccc(NS(C)(=O)=O)c1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.70
ALDH1A1 P00352 2/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
POLB P06746 1/20 0.61
KIF11 P52732 1/20 0.56
NR3C1 P04150 1/20 0.54
BRD4 O60885 2/20 0.53
HSD17B1 P14061 1/20 0.53
HSD17B2 P37059 1/20 0.53
NR3C2 P08235 1/20 0.52
HTT P42858 2/20 0.51
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
HPGD P15428 1/20 0.50
DHX9 Q08211 1/20 0.50
NPC1 O15118 1/20 0.50
JAK2 O60674 1/20 0.50
RAB9A P51151 1/20 0.50
KDM1A O60341 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1488105 0.91 KEAP1 (0.59) KEAP1ALDH1A1SMN1; SMN2POLBKIF11
SCHEMBL1488101 0.89 KEAP1 (0.57) KEAP1ALDH1A1SMN1; SMN2POLBKIF11
SCHEMBL9307018 0.87 KEAP1 (0.59) KEAP1ALDH1A1SMN1; SMN2POLBKIF11
SCHEMBL169803 0.87 KEAP1 (0.59) KEAP1ALDH1A1SMN1; SMN2POLBKIF11
SCHEMBL9865360 0.87 KEAP1 (0.59) KEAP1ALDH1A1SMN1; SMN2POLBKIF11
SCHEMBL14419962 0.86 KEAP1 (0.53) KEAP1ALDH1A1SMN1; SMN2POLBKIF11
SCHEMBL9479564 0.86 KEAP1 (0.64) KEAP1ALDH1A1SMN1; SMN2POLBNR3C1
SCHEMBL8390036 0.86 KEAP1 (0.53) KEAP1ALDH1A1SMN1; SMN2POLBKIF11
SCHEMBL9222851 0.86 KEAP1 (0.53) KEAP1ALDH1A1SMN1; SMN2POLBKIF11
SCHEMBL29794800 0.86 KEAP1 (0.53) KEAP1ALDH1A1SMN1; SMN2POLBKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4929530-A OXIDATIVE LEUCO DYES, PHOTO-OXIDIZERS, REDUCING AGENTS, ORGANIC SULFONAMIDES AND PHENOLIC COMPONENTS; EXPOSING TO LIGHT FUJI PHOTO FILM CO., LTD. (JP) 1990-05-29 US claimed
CN-109096152-B Preparation method of m-methanesulfonamido aniline 乐平市赛复乐医药化工有限公司 2021-01-08 CN disclosed
US-20140176653-A1 NOVEL COMPOUND HAVING MULTIMER STRUCTURE OF XANTHENE DERIVATIVE, COLORING COMPOSITION, INK FOR INKJET RECORDING, METHOD OF INKJET RECORDING, COLOR FILTER, AND COLOR TONER FUJIFILM CORPORATION (JP) 2014-06-26 US disclosed
EP-2423202-B1 Triazine-based compound and ultraviolet absorber FUJIFILM CORP (JP) 2013-01-16 EP disclosed
US-20120053343-A1 TRIAZINE-BASED COMPOUND AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2012-03-01 US disclosed
EP-2423202-A1 Triazine-based compound and ultraviolet absorber Fujifilm Corporation (JP) 2012-02-29 EP disclosed
US-7270703-B2 Metallized dyes having colorfastness, heat and ozone resistance, used for thermal printing, color filters, toners, liquid crystal displays and coloring fibers FUJIFILM CORPORATION (JP) 2007-09-18 US disclosed
US-7256222-B2 Radiation-curable ink composition and image recording method FUJIFILM CORPORATION (JP) 2007-08-14 US disclosed
US-7250079-B2 Coloring composition and inkjet recording method FUJIFILM CORPORATION (JP) 2007-07-31 US disclosed
US-7223453-B2 Ink jet recording medium and ink jet recording method FUJIFILM CORPORATION (JP) 2007-05-29 US disclosed
US-7219988-B2 Water-soluble phthalocyanine compound-containing ink for ink jetting, ink jet recording method and method for improving ozone gas discoloration of colored image material FUJI PHOTO FILM CO., LTD. (JP) 2007-05-22 US disclosed
US-5399455-A Electrophotographic toner composition and image fixing process FUJI XEROX CO., LTD. (JP) 1995-03-21 US disclosed
US-4929530-A OXIDATIVE LEUCO DYES, PHOTO-OXIDIZERS, REDUCING AGENTS, ORGANIC SULFONAMIDES AND PHENOLIC COMPONENTS; EXPOSING TO LIGHT FUJI PHOTO FILM CO., LTD. (JP) 1990-05-29 US disclosed
US-4824721-A CAPSULES OF OIL SOLUBLE DYES WHICH SWELL AND RELEASE DYE UPON HEATING FUJI PHOTO FILM CO., LTD. (JP) 1989-04-25 US disclosed
US-4758495-A Diazo microcapsule recording material prepared using ion exchange treatment FUJI PHOTO FILM CO., LTD. (JP) 1988-07-19 US disclosed
US-4749679-A Heat sensitive recording materials FUJI PHOTO FILM CO., LTD. (JP) 1988-06-07 US disclosed
EP-0262953-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-04-06 EP disclosed
US-4682194-A MICROCAPSULES CONTAINING LEUCO DYE FUJI PHOTO FILM CO., LTD. (JP) 1987-07-21 US disclosed
US-4644376-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120053343-A1 TRIAZINE-BASED COMPOUND AND ULTRAVIOLET ABSORBER H1-2, H1-0, CHRM1 KEAP1 2627/4885ALDH1A1 818/4885SMN1; SMN2 4185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.