Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988725 | 0.93 | KDM4C (0.50) | PTGDR2EPHX2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6989792 | 0.81 | MEN1 (0.45) | ALDH1A1MAPTL3MBTL1KDM4EKDM6B | |
| SCHEMBL6235622 | 0.80 | BRD4 (0.43) | ALDH1A1MAPTL3MBTL1KDM4EKDM6B | |
| SCHEMBL6985002 | 0.78 | KDM4E (0.42) | PTGDR2ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL5210605 | 0.77 | CFTR (0.55) | ALDH1A1MAPTL3MBTL1KDM4EKDM6B | |
| SCHEMBL16569986 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1KDM4EKDM6B | |
| SCHEMBL6232235 | 0.74 | KDM4A (0.43) | ALDH1A1MAPTL3MBTL1KDM4EKDM6B | |
| SCHEMBL6235620 | 0.74 | KDM4C (0.49) | ALDH1A1MAPTL3MBTL1KDM4EKDM6B | |
| SCHEMBL18864231 | 0.73 | MAPT (0.46) | ALDH1A1MAPTL3MBTL1POLBKDM4E | |
| SCHEMBL5808527 | 0.73 | ALDH1A1 (0.69) | ALDH1A1MAPTL3MBTL1KDM4EKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |