Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | TET3 | O43151 | 1/20 | 0.40 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.40 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.40 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235620 | 0.94 | KDM4C (0.49) | BRD4ALDH1A1MAPTL3MBTL1NR3C2 | |
| SCHEMBL6988726 | 0.80 | PTGDR2 (0.47) | ALDH1A1MAPTL3MBTL1ALKBH5FTO | |
| SCHEMBL5210605 | 0.76 | CFTR (0.55) | ALDH1A1MAPTL3MBTL1ALKBH5FTO | |
| SCHEMBL5808527 | 0.75 | ALDH1A1 (0.69) | ALDH1A1MAPTL3MBTL1ALKBH5FTO | |
| SCHEMBL5214358 | 0.75 | PPARG (0.55) | ALDH1A1MAPTL3MBTL1LMNAMAPK1 | |
| SCHEMBL6989792 | 0.74 | MEN1 (0.45) | ALDH1A1MAPTL3MBTL1ALKBH5FTO | |
| SCHEMBL6988725 | 0.74 | KDM4C (0.50) | ALDH1A1MAPTL3MBTL1ALKBH5FTO | |
| SCHEMBL6989789 | 0.73 | KDM4C (0.53) | ALDH1A1MAPTALKBH5FTOKDM5A | |
| SCHEMBL16569986 | 0.73 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1ALKBH5FTO | |
| SCHEMBL6987326 | 0.72 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1NR3C2ALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530467-A2 | COMBINATION OF AN ALLOSTERIC CARBOXYLIC INHIBITOR OF MATRIX METALLOPROTEINASE-13 WITH CELECOXIB OR VALDECOXIB | Warner-Lambert Company LLC (US) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004006912-A2 | COMBINATION OF AN ALLOSTERIC CARBOXYLIC INHIBITOR OF MATRIX METALLOPROTEINASE-13 WITH CELECOXIB OR VALDECOXIB | WARNER-LAMBERT COMPANY LLC (US) | 2004-01-22 | — | — | WO | disclosed |