Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 13/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 12/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27579769 | 0.79 | PPARG (0.36) | PIK3CBPIK3CGPIK3CDCA12CA1 | |
| SCHEMBL6986435 | 0.74 | TARBP2 (0.46) | — | |
| SCHEMBL6703700 | 0.74 | TARBP2 (0.46) | — | |
| SCHEMBL6993450 | 0.74 | FFAR2 (0.38) | — | |
| SCHEMBL27607598 | 0.74 | MAPT (0.36) | — | |
| SCHEMBL27597552 | 0.74 | UTRN (0.37) | — | |
| SCHEMBL6994309 | 0.73 | MAPT (0.41) | CA9 | |
| SCHEMBL6988862 | 0.72 | PPARG (0.38) | — | |
| SCHEMBL29104730 | 0.71 | APP (0.36) | CNR2 | |
| SCHEMBL4894750 | 0.70 | CA12 (0.41) | CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1578659-A | Modulators of peroxisome proliferator activated receptors (ppar) | LILLY CO ELI (US) | 2005-02-09 | — | — | CN | disclosed |
| CN-1471517-A | OXAZOLYL-arylpropionic acid derivatives and their sue as PPAR agonists | — | 2004-01-28 | — | — | CN | disclosed |
| EP-1313716-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002016331-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |