Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703700 | 0.89 | TARBP2 (0.46) | TARBP2MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL5218987 | 0.89 | TARBP2 (0.42) | TARBP2TP53KDM4EALDH1A1KMT2A | |
| SCHEMBL6988862 | 0.89 | PPARG (0.38) | TARBP2MAPTTP53KDM4EKMT2A | |
| SCHEMBL27607598 | 0.84 | MAPT (0.36) | MAPTTP53KDM4EALDH1A1KMT2A | |
| SCHEMBL6705288 | 0.83 | TARBP2 (0.39) | TARBP2TP53KDM4EALDH1A1KMT2A | |
| SCHEMBL6994309 | 0.79 | MAPT (0.41) | MAPTTP53KDM4EALDH1A1KMT2A | |
| SCHEMBL6990599 | 0.79 | FLT1 (0.38) | MAPTTP53KDM4EALDH1A1KMT2A | |
| SCHEMBL6993450 | 0.78 | FFAR2 (0.38) | RAB9ANPC1 | |
| SCHEMBL27597552 | 0.76 | UTRN (0.37) | MAPTTP53KDM4EALDH1A1KMT2A | |
| SCHEMBL6989034 | 0.74 | PIK3CB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1578659-A | Modulators of peroxisome proliferator activated receptors (ppar) | LILLY CO ELI (US) | 2005-02-09 | — | — | CN | disclosed |
| EP-1313715-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018355-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-03-07 | — | — | WO | disclosed |