Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 11/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703700 | 0.78 | TARBP2 (0.46) | FAAHNPC1RAB9A | |
| SCHEMBL6986435 | 0.78 | TARBP2 (0.46) | NPC1RAB9A | |
| SCHEMBL27607598 | 0.78 | MAPT (0.36) | NPC1RAB9A | |
| SCHEMBL6994309 | 0.77 | MAPT (0.41) | RAB9A | |
| SCHEMBL6989034 | 0.74 | PIK3CB (0.33) | — | |
| SCHEMBL27579769 | 0.74 | PPARG (0.36) | PTGS2NPC1RAB9A | |
| SCHEMBL6990599 | 0.72 | FLT1 (0.38) | NPC1RAB9A | |
| SCHEMBL27597552 | 0.71 | UTRN (0.37) | ELANERAB9A | |
| SCHEMBL5116367 | 0.70 | ALDH1A1 (0.41) | ELANE | |
| SCHEMBL28975568 | 0.65 | NPC1 (0.36) | PTGS2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313716-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002016331-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |