Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694717 | 0.88 | KDM4E (0.60) | FAAHMEN1KMT2AMAPTKDM4E | |
| SCHEMBL6698803 | 0.87 | FAAH (0.47) | FAAHMEN1KMT2AMAPTBCHE | |
| SCHEMBL6990296 | 0.86 | FAAH (0.55) | FAAHMEN1KMT2AMAPTBCHE | |
| SCHEMBL6695899 | 0.85 | KMT2A (0.61) | FAAHMEN1KMT2AMAPTGFER | |
| SCHEMBL6698763 | 0.83 | MEN1 (0.61) | FAAHMEN1KMT2APOLB | |
| SCHEMBL6702949 | 0.83 | HTT (0.53) | FAAHMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6699343 | 0.83 | EPHX2 (0.47) | FAAHMEN1KMT2AMAPTBCHE | |
| SCHEMBL6699018 | 0.81 | FAAH (0.55) | FAAHMEN1KMT2AMAPTKDM4E | |
| SCHEMBL6698809 | 0.81 | HTR7 (0.68) | FAAHMAPTHTR7GAA | |
| SCHEMBL6701308 | 0.77 | KDM4E (0.61) | MEN1KMT2AP2RX7KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1332127-A2 | AMIDINO-UREA SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SNYTHESIS | Warner-Lambert Company LLC (US) | 2003-08-06 | — | — | EP | disclosed |
| WO-2002036554-A2 | AMIDINO-UREA SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SNYTHESIS | WARNER-LAMBERT COMPANY LLC (US) | 2002-05-10 | — | — | WO | disclosed |