Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.68 |
| ▸ | DRD3 | P35462 | 6/20 | 0.56 |
| ▸ | DRD2 | P14416 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699018 | 0.86 | FAAH (0.55) | HTR7FAAHMAPT | |
| SCHEMBL6989152 | 0.81 | FAAH (0.54) | HTR7FAAHMAPTGAA | |
| SCHEMBL6698817 | 0.81 | HTR7 (1.00) | HTR7DRD3DRD2NPC1FAAH | |
| SCHEMBL6695899 | 0.81 | KMT2A (0.61) | FAAHMAPTGAA | |
| SCHEMBL6701693 | 0.80 | HTR7 (0.57) | HTR7DRD3DRD2NPC1FAAH | |
| SCHEMBL6698803 | 0.78 | FAAH (0.47) | FAAHMAPTGAA | |
| SCHEMBL6694717 | 0.76 | KDM4E (0.60) | HTR7FAAHHTR1AMAPTRAB9A | |
| SCHEMBL6990296 | 0.75 | FAAH (0.55) | FAAHMAPT | |
| SCHEMBL6699343 | 0.74 | EPHX2 (0.47) | FAAHMAPTGAA | |
| SCHEMBL6702816 | 0.73 | HTR1A (0.51) | HTR7DRD3DRD2NPC1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044037-A1 | Amidino-urea serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their snythesis | HONG YUFENG (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044037-A1 | Amidino-urea serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their snythesis | HTR7, HTR1A, HTR2C | HTR7 1/4885DRD3 300/4885DRD2 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.