Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22181066 | 0.78 | TERT (0.50) | PARP1HDAC6ACHEGAAMEN1 | |
| SCHEMBL24898418 | 0.77 | EPHX1 (0.43) | CES2CES1EPHX1PARP1HDAC1 | |
| SCHEMBL28476880 | 0.76 | ALDH1A1 (0.48) | PARP1GAAMAOBSMN1; SMN2 | |
| SCHEMBL28470876 | 0.76 | TERT (0.49) | PARP1TSHRGAAMEN1KMT2A | |
| SCHEMBL27548981 | 0.76 | ALDH1A1 (0.47) | TSHRSMN1; SMN2 | |
| SCHEMBL1162110 | 0.74 | HSD17B10 (0.66) | TSHRGAAMEN1KMT2A | |
| SCHEMBL15694511 | 0.74 | CES2 (0.42) | CES2CES1TSHRMEN1KMT2A | |
| SCHEMBL342299 | 0.73 | CA12 (0.54) | CES2CES1TSHRSMN1; SMN2 | |
| SCHEMBL1162251 | 0.73 | HPGD (0.44) | CES2CES1PARP1TSHR | |
| SCHEMBL19220610 | 0.73 | MAPT (0.44) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796383-B | 1-thiophenyl-N-acetyl-2-naphthylamine and its derivative and synthesis method | 湘潭大学 | 2020-09-18 | — | — | CN | claimed |
| CN-109796383-B | 1-thiophenyl-N-acetyl-2-naphthylamine and its derivative and synthesis method | 湘潭大学 | 2020-09-18 | — | — | CN | disclosed |
| EP-1345930-A2 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050067-A2 | PHARMACEUTICAL HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 2002-06-27 | — | — | WO | disclosed |