SCHEMBL698963

SCHEMBL698963

Cc1cccc(C(C)c2nccn2C(C)OC(=O)N2CCC[C@@]2(C)C(=O)O)c1C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 2/20 0.33
OPRK1 P41145 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL696009 0.77 HTR2C (0.38)
SCHEMBL697072 0.71 KDM4E (0.33)
SCHEMBL696280 0.70 ADRA2A (0.35) OPRD1OPRK1
SCHEMBL697071 0.70 KDM4E (0.32)
SCHEMBL698523 0.69 ADRA2C (0.41)
SCHEMBL698166 0.69 OPRD1 (0.33) OPRD1OPRK1
SCHEMBL704063 0.69 BRD4 (0.44) OPRD1OPRK1
SCHEMBL1573151 0.69 CYP26A1 (0.34)
SCHEMBL698416 0.69 CYP26A1 (0.34)
SCHEMBL697679 0.69 CYP26A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2423199-A1 Substituted imidazoles and their use as pesticides Pfizer Limited (GB) 2012-02-29 EP disclosed