Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methanesulfonamide SCHEMBL6999861 | 0.92 | CA2 (0.44) | SLC6A2SLC6A4GNAI3HTR2CL3MBTL1 | |
| Trifluoroacetamide SCHEMBL6993217 | 0.89 | SLC6A2 (0.40) | SLC6A2SLC6A4GNAI3SLC6A3L3MBTL1 | |
| SCHEMBL1596640 | 0.86 | SLC6A2 (0.40) | SLC6A2SLC6A4GNAI3HTR2CSLC6A3 | |
| SCHEMBL3048141 | 0.78 | HTR2C (0.55) | SLC6A2SLC6A4HTR2CSLC6A3KCNH2 | |
| SCHEMBL13701283 | 0.78 | HTR2C (0.55) | SLC6A2SLC6A4HTR2CSLC6A3KCNH2 | |
| SCHEMBL3048145 | 0.78 | HTR2C (0.55) | SLC6A2SLC6A4HTR2CSLC6A3KCNH2 | |
| SCHEMBL4225398 | 0.78 | HTR2C (0.55) | SLC6A2SLC6A4HTR2CSLC6A3KCNH2 | |
| SCHEMBL1596383 | 0.77 | SLC6A4 (0.42) | SLC6A2SLC6A4HTR2CSLC6A3KCNH2 | |
| SCHEMBL3159087 | 0.77 | SLC6A4 (0.42) | SLC6A2SLC6A4HTR2CSLC6A3KCNH2 | |
| SCHEMBL13701328 | 0.77 | GNAI3 (0.47) | SLC6A2SLC6A4GNAI3HTR2CL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6004982-A | SIDE EFFECT REDUCTION; SCHIZOPHRENIA | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |