Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209949 | 0.93 | L3MBTL1 (0.55) | L3MBTL1LMNAACHEMAPK1TP53 | |
| SCHEMBL1454525 | 0.91 | L3MBTL1 (0.57) | L3MBTL1LMNAMAPK1TDP1KMT2A | |
| SCHEMBL6989122 | 0.81 | LMNA (0.48) | L3MBTL1LMNAACHEMAPK1TDP1 | |
| SCHEMBL6995306 | 0.80 | LMNA (0.47) | L3MBTL1LMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9572368 | 0.79 | CYP3A4 (0.46) | L3MBTL1LMNAMAPK1TDP1KMT2A | |
| SCHEMBL5207507 | 0.79 | L3MBTL1 (0.59) | L3MBTL1LMNAMAPK1TDP1KMT2A | |
| SCHEMBL13557321 | 0.79 | L3MBTL1 (0.54) | L3MBTL1LMNAMAPK1TDP1KMT2A | |
| SCHEMBL27403581 | 0.79 | ALDH2 (0.54) | L3MBTL1LMNAKMT2AALDH2ALDH1A1 | |
| SCHEMBL14121604 | 0.79 | TP53 (0.52) | LMNAACHEMAPK1TP53KMT2A | |
| SCHEMBL14122295 | 0.79 | TP53 (0.52) | LMNAACHEMAPK1TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313717-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002016332-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |