Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 11/20 | 0.62 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.62 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989178 | 0.86 | AVPR2 (0.69) | AVPR2AVPR1AAVPR1BOXTR | |
| SCHEMBL6993361 | 0.86 | AVPR2 (0.57) | AVPR2AVPR1AAVPR1BMAPTTP53 | |
| SCHEMBL8819981 | 0.86 | AVPR2 (0.61) | AVPR2AVPR1AAVPR1BMEN1KMT2A | |
| SCHEMBL6994183 | 0.82 | AVPR2 (0.60) | AVPR2AVPR1AAVPR1BOXTR | |
| SCHEMBL6989393 | 0.80 | AVPR1A (0.66) | AVPR2AVPR1AAVPR1BMAPTTP53 | |
| SCHEMBL6987523 | 0.78 | AVPR2 (0.56) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL8797804 | 0.76 | AVPR1A (1.00) | AVPR2AVPR1AAVPR1BOXTR | |
| SCHEMBL8820810 | 0.76 | AVPR2 (0.62) | AVPR2AVPR1AOXTR | |
| SCHEMBL6988903 | 0.75 | AVPR2 (0.55) | AVPR2AVPR1AAVPR1BMAPTTP53 | |
| SCHEMBL6989777 | 0.74 | AVPR2 (0.58) | AVPR2AVPR1AAVPR1BTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |