Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 7/20 | 0.57 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.57 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989777 | 0.89 | AVPR2 (0.58) | AVPR2AVPR1AAVPR1BTP53LMNA | |
| SCHEMBL6989953 | 0.86 | AVPR2 (0.62) | AVPR2AVPR1AAVPR1BTP53MAPT | |
| SCHEMBL6988080 | 0.86 | AVPR2 (0.61) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL8819934 | 0.83 | AVPR2 (0.55) | AVPR2AVPR1AAVPR1BTP53MAPT | |
| SCHEMBL6991662 | 0.81 | AVPR1A (0.58) | AVPR2AVPR1AAVPR1BTP53LMNA | |
| SCHEMBL6995626 | 0.81 | AVPR1A (0.57) | AVPR2AVPR1AAVPR1BTP53MAPT | |
| SCHEMBL6992837 | 0.80 | AVPR2 (0.57) | AVPR2AVPR1AAVPR1BTP53LMNA | |
| SCHEMBL6985550 | 0.78 | AVPR2 (0.47) | AVPR2AVPR1AAVPR1BKMT2A | |
| SCHEMBL8820801 | 0.76 | AVPR2 (0.50) | AVPR2AVPR1AAVPR1BTP53LMNA | |
| SCHEMBL6987427 | 0.75 | AVPR1A (0.59) | AVPR2AVPR1AAVPR1BTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |