Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 8/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.48 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994183 | 0.89 | AVPR2 (0.60) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL8797460 | 0.88 | AVPR1A (0.62) | AVPR2LMNATP53AVPR1AAVPR1B | |
| SCHEMBL6989178 | 0.86 | AVPR2 (0.69) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6990759 | 0.81 | AVPR1A (0.68) | AVPR2AVPR1AAVPR1BMEN1KMT2A | |
| SCHEMBL6987519 | 0.80 | AVPR1A (0.63) | AVPR2LMNATP53AVPR1AAVPR1B | |
| SCHEMBL6988080 | 0.79 | AVPR2 (0.61) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL5321445 | 0.79 | AVPR1A (0.75) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6996850 | 0.78 | LMNA (0.51) | AVPR2LMNATP53AVPR1AAVPR1B | |
| SCHEMBL6995228 | 0.77 | AVPR2 (0.51) | AVPR2AVPR1AAVPR1BHDAC1HDAC6 | |
| SCHEMBL6989953 | 0.75 | AVPR2 (0.62) | AVPR2LMNATP53AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |