Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527236 | 0.85 | CHRNB2 (0.35) | ATM | |
| SCHEMBL572568 | 0.85 | KDM4E (0.38) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL7817864 | 0.85 | KDM4E (0.38) | KDM4EMAPTKMT2AATMCYP2D6 | |
| Hydrochloric Acid SCHEMBL538525 | 0.84 | DPP4 (0.31) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL5892838 | 0.83 | SLC6A1 (0.34) | KDM4EMAPTKMT2AATMCYP2D6 | |
| Water SCHEMBL7151392 | 0.83 | KDM4E (0.37) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL27701676 | 0.83 | SLC6A1 (0.34) | KDM4EMAPTKMT2AATMCYP2D6 | |
| Piperazine SCHEMBL28147717 | 0.81 | CHRNB2 (0.33) | ATMCA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL27824226 | 0.81 | SLC6A1 (0.33) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL8498877 | 0.81 | HTR2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |