SCHEMBL6990045

SCHEMBL6990045

CC1c2ccccc2CCN1c1nc(Cl)nc2c1CCCC2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 1/20 0.37
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
LIPE Q05469 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
CHRM1 P11229 1/20 0.33
ADRA1D P25100 1/20 0.33
ADRA1A P35348 1/20 0.33
ADRA1B P35368 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
HTR3E A5X5Y0 1/20 0.33
HTR3B O95264 1/20 0.33
HTR3A P46098 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8573668 0.82 DRD1 (0.38) DRD1ALDH1A1HPGDLIPEMEN1
Hydrochloric Acid SCHEMBL6997882 0.80 NPC1 (0.36) ALDH1A1HPGDMEN1KMT2AHTR3E
SCHEMBL6957781 0.79 DRD1 (0.39) DRD1LIPELMNACHRNA7RIPK1
SCHEMBL6995013 0.79 DRD1 (0.39) DRD1LIPELMNACHRNA7RIPK1
SCHEMBL7000740 0.79 DRD1 (0.39) DRD1LIPELMNACHRNA7RIPK1
Hydrochloric Acid SCHEMBL6997879 0.79 CCNA2 (0.47) MEN1KMT2ALMNAMAPTHTT
SCHEMBL7824698 0.78 EGFR (0.43) DRD1ALDH1A1HPGDLIPEHTR3E
SCHEMBL8572580 0.77 ALDH1A1 (0.36) DRD1ALDH1A1HPGDLIPEMEN1
SCHEMBL6989000 0.75 DRD1 (0.39) DRD1LIPEGRIN1GRIN2B
SCHEMBL6998861 0.75 CCNA2 (0.36) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0775120-B1 NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2003-06-04 EP disclosed
US-5750531-A ANTISECRETORY AGENTS FOR THE TREATMENT OF PEPTIC ULCER YUHAN CORPORATION (KR) 1998-05-12 US disclosed
EP-0775120-A1 NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF Yuhan Corporation (KR) 1997-05-28 EP disclosed
WO-1996005177-A1 NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 1996-02-22 WO disclosed