Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 3/20 | 0.34 |
| ▸ | PRCP | P42785 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7000740 | 1.00 | DRD1 (0.39) | DRD1LIPESPRPRCPTRPM8 | |
| SCHEMBL6957781 | 1.00 | DRD1 (0.39) | DRD1LIPESPRPRCPTRPM8 | |
| SCHEMBL15672478 | 0.87 | DRD1 (0.36) | DRD1LIPESPRPRCPTRPM8 | |
| SCHEMBL6989000 | 0.85 | DRD1 (0.39) | DRD1LIPESPRPRCPTRPM8 | |
| SCHEMBL6157859 | 0.85 | HTR2A (0.37) | — | |
| SCHEMBL6159540 | 0.85 | HTR2A (0.36) | — | |
| SCHEMBL17779787 | 0.85 | HRH4 (0.38) | DRD1LIPESPRPRCPLMNA | |
| SCHEMBL6157563 | 0.83 | HTR2A (0.36) | — | |
| SCHEMBL6160361 | 0.83 | ESR1 (0.34) | — | |
| SCHEMBL6958205 | 0.83 | DRD1 (0.37) | DRD1LIPESPRPRCPTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775120-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2003-06-04 | — | — | EP | disclosed |
| US-5750531-A | ANTISECRETORY AGENTS FOR THE TREATMENT OF PEPTIC ULCER | YUHAN CORPORATION (KR) | 1998-05-12 | — | — | US | disclosed |
| EP-0775120-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005177-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1996-02-22 | — | — | WO | disclosed |