Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17800068 | 0.84 | PRCP (0.47) | EGFRTUBB4ATUBBPDGFRBTUBA3C | |
| SCHEMBL7810189 | 0.81 | EHMT2 (0.38) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6995013 | 0.81 | DRD1 (0.39) | DRD1LMNAMAPK1LIPEPRCP | |
| SCHEMBL6957781 | 0.81 | DRD1 (0.39) | DRD1LMNAMAPK1LIPEPRCP | |
| SCHEMBL7000740 | 0.81 | DRD1 (0.39) | DRD1LMNAMAPK1LIPEPRCP | |
| SCHEMBL7811938 | 0.81 | ADORA2A (0.42) | DRD1ALDH1A1LMNAKDM4EGAA | |
| SCHEMBL7811946 | 0.81 | ADORA2A (0.42) | DRD1ALDH1A1LMNAKDM4EGAA | |
| SCHEMBL7821140 | 0.81 | ADORA2A (0.42) | DRD1ALDH1A1LMNAKDM4EGAA | |
| Hydrochloric Acid SCHEMBL7819979 | 0.80 | EHMT2 (0.38) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6990045 | 0.78 | DRD1 (0.37) | DRD1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677049-B1 | QUINAZOLINE DERIVATIVES | YUHAN CORP LTD (KR) | 2001-07-25 | — | — | EP | disclosed |
| US-5686458-A | Quinazoline deriviates for treating peptic ulcer | YUHAN CORPORATION (KR) | 1997-11-11 | — | — | US | disclosed |