Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994309 | 0.91 | MAPT (0.41) | CA2CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL6705288 | 0.87 | TARBP2 (0.39) | KMT2ANPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL5218987 | 0.84 | TARBP2 (0.42) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL6988862 | 0.84 | PPARG (0.38) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL6703700 | 0.83 | TARBP2 (0.46) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL6986435 | 0.79 | TARBP2 (0.46) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL28357540 | 0.78 | ALDH1A1 (0.42) | CA2CA9CA1KMT2AHDAC3 | |
| SCHEMBL27607598 | 0.76 | MAPT (0.36) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL5208226 | 0.74 | PPARA (0.44) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL6992531 | 0.73 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313717-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002016332-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |