Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 12/20 | 0.41 |
| ▸ | TP53 | P04637 | 5/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL634168 | 0.83 | TARBP2 (0.42) | ALDH1A1KDM4EMAPTTP53POLB | |
| SCHEMBL27559786 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTTP53POLB | |
| SCHEMBL6994309 | 0.82 | MAPT (0.41) | ALDH1A1KDM4EMAPTTP53THRB | |
| SCHEMBL6990599 | 0.73 | FLT1 (0.38) | ALDH1A1KDM4EMAPTTP53THRB | |
| SCHEMBL6991142 | 0.72 | KDM4E (0.37) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL4021097 | 0.70 | EDNRA (0.44) | ALDH1A1KDM4EMAPTTP53POLB | |
| SCHEMBL9411853 | 0.69 | MAPT (0.41) | ALDH1A1MAPTTP53POLBKMT2A | |
| SCHEMBL4898554 | 0.67 | MAPT (0.50) | ALDH1A1KDM4EMAPTTP53THRB | |
| SCHEMBL23174731 | 0.67 | CCR1 (0.39) | ALDH1A1KDM4EMAPTTP53THRB | |
| SCHEMBL23174762 | 0.67 | ALPL (0.36) | ALDH1A1MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313716-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002016331-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |