Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289580 | 0.89 | HTR1A (0.55) | HTR1ADRD2SLC6A4 | |
| SCHEMBL8556391 | 0.86 | ADRA1D (0.74) | HTR1AADRA1DSLC6A4 | |
| SCHEMBL8558622 | 0.84 | HTR1A (0.73) | HTR1ADRD2ADRA1DSLC6A4 | |
| SCHEMBL11217122 | 0.84 | HTR1A (0.62) | HTR1ADRD2ADRA1DSLC6A4 | |
| SCHEMBL8554922 | 0.82 | ADRA1D (0.73) | HTR1AADRA1DSLC6A4 | |
| SCHEMBL8555085 | 0.82 | HTR1A (0.73) | HTR1ADRD2ADRA1DSLC6A4 | |
| SCHEMBL6991477 | 0.81 | DRD2 (0.71) | HTR1ADRD2ADRA1DSLC6A4 | |
| SCHEMBL9367741 | 0.81 | HTR1A (0.74) | HTR1ADRD2SLC6A4 | |
| SCHEMBL8558005 | 0.81 | HTR1A (0.77) | HTR1ADRD2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11222340 | 0.80 | DRD2 (0.70) | HTR1ADRD2ADRA1DSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207677-B1 | ADMINISERING SIGMA RECEPTOR BINDING PIPERIDINE DERIVATIVE FOR TREATING ANXIETY, EPILEPSY, CONVULSION, MOVEMENT DISORDER, AMNESIA | H. LUNDBECK A/S (DK) | 2001-03-27 | — | — | US | claimed |
| EP-0859004-B1 | Piperidine derivatives having anxiolytic effect | LUNDBECK & CO AS H (DK) | 2003-05-02 | — | — | EP | disclosed |
| US-6207677-B1 | ADMINISERING SIGMA RECEPTOR BINDING PIPERIDINE DERIVATIVE FOR TREATING ANXIETY, EPILEPSY, CONVULSION, MOVEMENT DISORDER, AMNESIA | H. LUNDBECK A/S (DK) | 2001-03-27 | — | — | US | disclosed |
| US-6031099-A | Piperidine derivates having anxiolytic effect | H. LUNDBECK A/S (DK) | 2000-02-29 | — | — | US | disclosed |
| EP-0859004-A1 | Piperidine derivatives having anxiolytic effect | H. LUNDBECK A/S (DK) | 1998-08-19 | — | — | EP | disclosed |
| EP-0853085-A1 | Piperidine derivatives having anxiolytic effect | H. LUNDBECK A/S (DK) | 1998-07-15 | — | — | EP | disclosed |
| US-5665725-A | Piperidine derivatives having anxiolytic effect | Lundbeck, H. (DK) | 1997-09-09 | — | — | US | disclosed |
| EP-0518805-A1 | Piperidine derivatives | H. LUNDBECK A/S (DK) | 1992-12-16 | — | — | EP | disclosed |