Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 2/20 | 0.37 |
| ▸ | CDK8 | P49336 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987821 | 0.80 | DAPK3 (0.42) | CCNCCDK8HTT | |
| SCHEMBL29159564 | 0.72 | CDK8 (0.47) | CCNCCDK8MEN1KMT2AKDM4E | |
| SCHEMBL28481352 | 0.69 | POLB (0.46) | MEN1KMT2AKDM4EPOLBHCAR2 | |
| SCHEMBL28474258 | 0.69 | MEN1 (0.31) | MEN1KMT2AKDM4E | |
| SCHEMBL9572445 | 0.68 | KMT2A (0.58) | MEN1KMT2AMAPT | |
| SCHEMBL29154147 | 0.65 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL28998209 | 0.65 | MEN1 (0.43) | CDK8MEN1KMT2AMAPT | |
| SCHEMBL4491547 | 0.65 | SIRT3 (0.42) | CCNCCDK8KDM4EPOLBHCAR2 | |
| SCHEMBL19066140 | 0.65 | KDM4E (0.36) | MEN1KMT2AKDM4EHTT | |
| SCHEMBL15775500 | 0.64 | HSD17B10 (0.56) | KDM4EPOLBHCAR2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268469-A1 | N-(HETEROCYCLYL)BENZENE OR PYRIDINE SULPHONAMIDES AS ANTITHROMBOTIC AGENTS AND ANTICOAGULANTS | SANOFI-SYNTHELABO (FR) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001070736-A1 | N-(HETEROCYCLYL)BENZENE OR PYRIDINE SULPHONAMIDES AS ANTITHROMBOTIC AGENTS AND ANTICOAGULANTS | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | disclosed |