Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NNMT | P40261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27912644 | 0.81 | CTSL (0.33) | — | |
| SCHEMBL1082935 | 0.81 | SIRT6 (0.42) | SIRT6KDM4ENNMT | |
| SCHEMBL29163356 | 0.81 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL15881205 | 0.77 | CDK2 (0.42) | MEN1KMT2ASIRT6 | |
| SCHEMBL5200121 | 0.73 | MEN1 (0.44) | MEN1KMT2ANNMT | |
| SCHEMBL29184514 | 0.73 | KIF11 (0.37) | KMT2A | |
| SCHEMBL29167770 | 0.73 | AURKA (0.31) | — | |
| SCHEMBL28626950 | 0.71 | SIRT6 (0.43) | MEN1KMT2ASIRT6NNMT | |
| SCHEMBL421693 | 0.70 | — | — | |
| SCHEMBL6990968 | 0.69 | CCNC (0.37) | MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107746405-B | SYK inhibitors | 吉利德科学公司 | 2020-09-22 | — | — | CN | disclosed |