Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697825 | 0.88 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2TP53POLB | |
| SCHEMBL697921 | 0.85 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2P2RX7MEN1 | |
| SCHEMBL697274 | 0.83 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL699102 | 0.81 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2P2RX7MEN1 | |
| SCHEMBL697255 | 0.79 | MEN1 (0.46) | RAB9ANPC1SMN1; SMN2TP53RXFP1 | |
| SCHEMBL697005 | 0.78 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2P2RX7MEN1 | |
| SCHEMBL696264 | 0.75 | TP53 (0.42) | TP53POLBRXFP1P2RX7MEN1 | |
| SCHEMBL5851274 | 0.74 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2TP53MEN1 | |
| SCHEMBL697875 | 0.73 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL699209 | 0.73 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2ALDH1A1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| CN-101370786-B | Substituted imidazoles and their use as pesticides | PFIZER | 2012-01-11 | — | — | CN | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |
| CN-101370786-A | Substituted imidazoles and their use as pesticides | PFIZER LTD (GB) | 2009-02-18 | — | — | CN | disclosed |