SCHEMBL6991478

SCHEMBL6991478

COP(=O)(OC)OCC(C)=O

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
ALDH1A1 P00352 4/20 0.33
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
ACHE P22303 1/20 0.33
CES2 O00748 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6228266 0.87 TSHR (0.43) MGAMGAASIMGAM2ALDH1A1
SCHEMBL10476512 0.80 TSHR (0.36) ALDH1A1TSHRLMNACYP3A4ALOX15
SCHEMBL17482402 0.78 PLA2G2A (0.39) MGAMGAASIMGAM2CES2
SCHEMBL10010047 0.78 TSHR (0.42) MGAMGAASIMGAM2ALDH1A1
SCHEMBL27771235 0.78 TSHR (0.62) ALDH1A1TSHRLMNACYP3A4ACHE
SCHEMBL4818863 0.78 BTN3A1 (0.35) ALDH1A1TSHRLMNACYP3A4ALOX15
SCHEMBL3398971 0.78 MGAM (0.33) MGAMGAASIMGAM2CES2
SCHEMBL5596742 0.78 ACHE (0.32) ALDH1A1TSHRACHE
SCHEMBL5596547 0.78 PAOX (0.36) ALDH1A1ACHE
SCHEMBL11908881 0.76 ALDH1A1 (0.39) MGAMGAASIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112898340-B FSO (FSO)2N3Application in preparation of diazonium reagent 上海大学 2024-08-16 CN claimed
CN-117326905-A Synthesis method of (trans ) -4-ethyl-4 '-propyl-1, 1' -bicyclohexane 江苏广域化学有限公司 2024-01-02 CN claimed
CN-117326908-A Synthesis method of (trans ) -4-ethyl-4 '- (2-propylene) -1,1' -bicyclohexane 江苏广域化学有限公司 2024-01-02 CN claimed
CN-113045426-B Synthesis method of dihydropyridine drug degradation impurities 济南良福精合医药科技有限公司 2023-03-21 CN claimed
CN-113045426-A Synthesis method of dihydropyridine drug degradation impurities 济南纽华医药科技有限公司 2021-06-29 CN claimed
CN-112898340-A FSO (free space optical output)2N3Application in preparing diazo reagent 上海大学 2021-06-04 CN claimed
CN-103145540-B The preparation method of a kind of optical activity 7-halo-6-hydroxyl-heptan-3-alkene-2-ketone FUDAN UNIVERSITY (CN) 2015-07-29 CN claimed
CN-103724211-A Preparation method for m-aminophenylacetylene CHONGQING WORLD HAORUI PHARM CHEM CO LTD 2014-04-16 CN claimed
CN-103145540-A Preparation method of optically-active 7-halogenated-6-hydroxyheptane-3-ethylene-2-ketone UNIV FUDAN 2013-06-12 CN claimed
CN-103102256-A Preparation method of optical-activity 7-substituted oxy-6-hydroxyhept-3-ethylene-2-ketone UNIV FUDAN 2013-05-15 CN claimed
JP-7179483-A None JP disclosed
CN-112898340-B FSO (FSO)2N3Application in preparation of diazonium reagent 上海大学 2024-08-16 CN disclosed
CN-112898340-B FSO (FSO)2N3Application in preparation of diazonium reagent 上海大学 2024-08-16 CN disclosed
CN-117326908-A Synthesis method of (trans ) -4-ethyl-4 '- (2-propylene) -1,1' -bicyclohexane 江苏广域化学有限公司 2024-01-02 CN disclosed
CN-117326905-A Synthesis method of (trans ) -4-ethyl-4 '-propyl-1, 1' -bicyclohexane 江苏广域化学有限公司 2024-01-02 CN disclosed
EP-0750618-B1 OXAZOLIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM UPJOHN CO (US) 2003-02-19 EP disclosed
US-5668286-A ANTIBIOTIC PHARMACIA & UPJOHN COMPANY (US) 1997-09-16 US disclosed
EP-0750618-A1 OXAZOLIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PHARMACIA & UPJOHN COMPANY (US) 1997-01-02 EP disclosed
WO-1995025106-A1 OXAZOLIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PHARMACIA & UPJOHN COMPANY (US) 1995-09-21 WO disclosed
JP-H07179483-A PRODUCTION OF OPTICALLY ACTIVE PHOSPHONATE TAKASAGO INTERNATL CORP 1995-07-18 JP disclosed