SCHEMBL6991659

SCHEMBL6991659

CN1CCCC(C(=O)NC(=O)O)C1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
ITGB3 P05106 1/20 0.42
ITGA2B P08514 1/20 0.42
F2R P25116 1/20 0.42
LMNA P02545 1/20 0.41
BCHE P06276 2/20 0.40
TSHR P16473 1/20 0.40
PKM P14618 1/20 0.39
HTT P42858 1/20 0.39
KDM4E B2RXH2 2/20 0.38
POLB P06746 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPR1 P16066 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2600287 0.81 BCHE (0.56) ALDH1A1ITGB3ITGA2BF2RLMNA
SCHEMBL26971791 0.81 BCHE (0.56) ALDH1A1ITGB3ITGA2BF2RLMNA
SCHEMBL6582811 0.80 BCHE (0.41) ALDH1A1ITGB3ITGA2BF2RLMNA
SCHEMBL2600259 0.80 BCHE (0.41) ALDH1A1ITGB3ITGA2BF2RLMNA
SCHEMBL19550801 0.80 BCHE (0.41) ALDH1A1ITGB3ITGA2BF2RLMNA
SCHEMBL689749 0.79 ALDH1A1 (0.62) ALDH1A1LMNATSHRHTTKDM4E
SCHEMBL805212 0.79 ALDH1A1 (0.62) ALDH1A1LMNATSHRHTTKDM4E
SCHEMBL2637184 0.79 ALDH1A1 (0.62) ALDH1A1LMNATSHRHTTKDM4E
SCHEMBL13045996 0.79 BCHE (0.43) ALDH1A1ITGB3ITGA2BF2RLMNA
SCHEMBL3315913 0.79 TSHR (0.62) ITGB3ITGA2BF2RBCHETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0874809-B1 CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS SMITHKLINE BEECHAM PLC (GB) 2003-08-27 EP claimed
US-6239175-B1 Carbamoyloxy derivatives of mutiline and their use as antibacterials SMITHKLINE BEECHAM P.L.C. (GB) 2001-05-29 US claimed
EP-0874809-B1 CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS SMITHKLINE BEECHAM PLC (GB) 2003-08-27 EP disclosed
EP-0934316-B1 AZABICYCLIC CARBAMOYLOXY MUTILIN DERIVATIVES FOR ANTIBACTERIAL USE SMITHKLINE BEECHAM PLC (GB) 2002-10-16 EP disclosed
US-6239175-B1 Carbamoyloxy derivatives of mutiline and their use as antibacterials SMITHKLINE BEECHAM P.L.C. (GB) 2001-05-29 US disclosed
US-6121281-A Azabicyclic carbamoyloxy mutilin derivatives for antibacterial use SMITHKLINE BEECHAM P.L.C. (GB) 2000-09-19 US disclosed
US-6020368-A MICROBIOCIDES HINKS JEREMY DAVID (US) 2000-02-01 US disclosed
EP-0934316-A1 AZABICYCLIC CARBAMOYLOXY MUTILIN DERIVATIVES FOR ANTIBACTERIAL USE SMITHKLINE BEECHAM PLC (GB) 1999-08-11 EP disclosed
EP-0874809-A1 CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS SMITHKLINE BEECHAM PLC (GB) 1998-11-04 EP disclosed
WO-1998005659-A1 AZABICYCLIC CARBAMOYLOXY MUTILIN DERIVATIVES FOR ANTIBACTERIAL USE SMITHKLINE BEECHAM PLC (GB) 1998-02-12 WO disclosed
WO-1997025309-A1 CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS SMITHKLINE BEECHAM PLC (GB) 1997-07-17 WO disclosed