Sugi Predict

Sugi Predict / Compounds / SCHEMBL805212

SCHEMBL805212

SCHEMBL805212

CN1CCC[C@H](C(=O)O)C1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.62
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ KMT2A Q03164 2/20 0.46
▸ HSD17B10 Q99714 2/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ LMNA P02545 2/20 0.43
▸ SLC6A1 P30531 3/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ CYP2D6 P10635 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ TSHR P16473 1/20 0.41
▸ NFKB1 P19838 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ GRM3 Q14832 1/20 0.40
▸ HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2637184 1.00 ALDH1A1 (0.62) ALDH1A1SMN1; SMN2KMT2AHSD17B10KDM4E
SCHEMBL689749 1.00 ALDH1A1 (0.62) ALDH1A1SMN1; SMN2KMT2AHSD17B10KDM4E
Hydrochloric Acid SCHEMBL9762430 0.98 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2KMT2AHSD17B10KDM4E
Hydrochloric Acid SCHEMBL9761871 0.98 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2KMT2AHSD17B10KDM4E
Hydrochloric Acid SCHEMBL1130360 0.98 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2KMT2AHSD17B10KDM4E
SCHEMBL18625014 0.94 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2KMT2AHSD17B10KDM4E
SCHEMBL9867000 0.91 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2KMT2AHSD17B10KDM4E
SCHEMBL16002857 0.88 LMNA (0.54) ALDH1A1SMN1; SMN2KMT2AKDM4ELMNA
SCHEMBL16751013 0.88 LMNA (0.54) ALDH1A1SMN1; SMN2KMT2AKDM4ELMNA
SCHEMBL16750977 0.88 LMNA (0.54) ALDH1A1SMN1; SMN2KMT2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115151544-B Beta-lactamase inhibitor and preparation thereof 宁夏农林科学院 2024-08-16 — — CN disclosed
US-20230365561-A1 BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) 2023-11-16 — — US disclosed
US-20230365561-A1 BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) 2023-11-16 — — US disclosed
EP-4161921-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-04-12 — — EP disclosed
CN-115916776-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2023-04-04 — — CN disclosed
EP-4146650-A1 BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION Ningxia Academy of Agriculture and Forestry Sciences (CN) 2023-03-15 — — EP disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 — — US disclosed
CN-115151544-A Beta-lactamase inhibitors and preparation thereof 宁夏农林科学院 2022-10-04 — — CN disclosed
WO-2022047603-A1 BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) 2022-03-10 — — WO disclosed
WO-2021183370-A1 COMPOUNDS WITH IMMUNOMODULATORY ACTIVITY AND THERAPEUTIC USES THEREOF PURDUE RESEARCH FOUNDATION (US) 2021-09-16 — — WO disclosed
US-20080045533-A1 Novel cyclohexyl sulphones CHURCHER IAN 2008-02-21 — — US disclosed
US-20080045533-A1 Novel cyclohexyl sulphones CHURCHER IAN 2008-02-21 — — US disclosed
US-7304094-B2 Alzheimer's disease, modulate the processing of amyloid precursor protein by gamma-secretase MERCK SHARP + DOHME 2007-12-04 — — US disclosed
US-7304094-B2 Alzheimer's disease, modulate the processing of amyloid precursor protein by gamma-secretase MERCK SHARP + DOHME 2007-12-04 — — US disclosed
US-20070213329-A1 Sulphones which modulate the action of gammasecretase MERCK SHARP & DOHME (UK) LIMITED (GB) 2007-09-13 — — US disclosed
US-20070213329-A1 Sulphones which modulate the action of gammasecretase MERCK SHARP & DOHME (UK) LIMITED (GB) 2007-09-13 — — US disclosed
US-20070049581-A1 Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-03-01 — — US disclosed
EP-1070708-B1 Triazole derivatives HOFFMANN LA ROCHE (CH) 2004-01-14 — — EP disclosed
US-6265426-B1 CENTRAL NERVOUS SYSTEM DISORDERS HOFFMANN-LA ROCHE INC. 2001-07-24 — — US disclosed
EP-1070708-A1 Triazole and imidazole derivatives F. HOFFMANN-LA ROCHE AG (CH) 2001-01-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080045533-A1 Novel cyclohexyl sulphones BACE1, APP, PSEN1 ALDH1A1 2062/4885SMN1; SMN2 1271/4885KMT2A 4310/4885
US-20230365561-A1 BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION MGAM, LCT, GANAB ALDH1A1 315/4885SMN1; SMN2 3622/4885KMT2A 1197/4885
US-20070049581-A1 Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions CALCRL, CALCR, CALCA ALDH1A1 2010/4885SMN1; SMN2 4312/4885KMT2A 4791/4885
US-20070213329-A1 Sulphones which modulate the action of gammasecretase BACE1, PSEN1, BACE2 ALDH1A1 1019/4885SMN1; SMN2 1751/4885KMT2A 3319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.