SCHEMBL689749

SCHEMBL689749

CN1CCCC(C(=O)O)C1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
SMN1; SMN2 Q16637 2/20 0.50
KMT2A Q03164 2/20 0.46
HSD17B10 Q99714 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
LMNA P02545 2/20 0.43
SLC6A1 P30531 3/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
CYP2C19 P33261 1/20 0.41
MAPT P10636 1/20 0.41
GRM3 Q14832 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2637184 1.00 ALDH1A1 (0.62) ALDH1A1SMN1; SMN2KMT2AHSD17B10KDM4E
SCHEMBL805212 1.00 ALDH1A1 (0.62) ALDH1A1SMN1; SMN2KMT2AHSD17B10KDM4E
Hydrochloric Acid SCHEMBL9762430 0.98 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2KMT2AHSD17B10KDM4E
Hydrochloric Acid SCHEMBL9761871 0.98 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2KMT2AHSD17B10KDM4E
Hydrochloric Acid SCHEMBL1130360 0.98 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2KMT2AHSD17B10KDM4E
SCHEMBL18625014 0.94 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2KMT2AHSD17B10KDM4E
SCHEMBL9867000 0.91 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2KMT2AHSD17B10KDM4E
SCHEMBL16002857 0.88 LMNA (0.54) ALDH1A1SMN1; SMN2KMT2AKDM4ELMNA
SCHEMBL16751013 0.88 LMNA (0.54) ALDH1A1SMN1; SMN2KMT2AKDM4ELMNA
SCHEMBL16750977 0.88 LMNA (0.54) ALDH1A1SMN1; SMN2KMT2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 666 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3504194-A1 N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE Novartis AG (CH) 2019-07-03 EP claimed
WO-2018042316-A1 N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE NOVARTIS AG (CH) 2018-03-08 WO claimed
CN-106986789-A Hydroquinone compound and preparation method thereof and the application in antitumor or immunological regulation 中国人民解放军军事医学科学院生物医学分析中心 2017-07-28 CN claimed
EP-2617779-B1 Low odor environmentally-friendly nano-pigment inkjet ink composition JETBEST CORP (TW) 2014-11-05 EP claimed
CN-102770182-B Substituted isoquinolinones and quinazolinones NOVARTIS AG (CH) 2014-10-29 CN claimed
EP-2516009-B1 SUBSTITUTED ISOQUINOLINONES AND QUINAZOLINONES NOVARTIS AG (CH) 2014-09-24 EP claimed
US-20130029971-A1 CXCR3 RECEPTOR ANTAGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-01-31 US claimed
EP-1678147-B1 PHARMACEUTICALLY ACTIVE 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS MODULATORS OF PROTEIN KINASES LEAD DISCOVERY CENTER GMBH (DE) 2012-08-08 EP claimed
US-20090221581-A1 Methods of treating pain ASTRAZENECA AB (SE) 2009-09-03 US claimed
EP-1901747-A2 PYRIMIDINE-BASED CDK INHIBITORS FOR TREATING PAIN Ingenium Pharmaceuticals AG (DE) 2008-03-26 EP claimed
WO-2007053773-A1 COMPOSITIONS AND METHODS USING NICOTINIC ACID FOR TREATMENT OF HYPERCHOLESTEROLEMIA, HYPERLIPIDEMIA AND CARDIOVASCULAR DISEASE HENDRIX CURT (US) 2007-05-10 WO claimed
US-20070105793-A1 Compositions and methods using nicotinic acid for treatment of hypercholesterolemia, hyperlipidemia nd cardiovascular disease CONCOURSE HEALTH SCIENCES LLC 2007-05-10 US claimed
WO-2006125616-A2 PYRIMIDINE-BASED CDK INHIBITORS FOR TREATING PAIN INGENIUM PHARMACEUTICALS AG (DE) 2006-11-30 WO claimed
EP-1678147-A1 PHARMACEUTICALLY ACTIVE 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS MODULATORS OF PROTEIN KINASES GPC Biotech AG (DE) 2006-07-12 EP claimed
EP-1575947-A1 2-OXOPYRIDIN-3-YL THIA(DI)AZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CELL PROLIFERATION AND APOPTOSIS RELATED DISEASES Amgen Inc. (US) 2005-09-21 EP claimed
WO-2005026129-A1 PHARMACEUTICALLY ACTIVE 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS MODULATORS OF PROTEIN KINASES GPC BIOTECH AG (DE) 2005-03-24 WO claimed
WO-2004113353-A1 SILICON-COMPRISING AMINOTHIAZOLE DERIVATIVES AS CDK INHIBITORS AMEDIS PHARMACEUTICALS LTD. (GB) 2004-12-29 WO claimed
WO-2004060890-A1 2-OXOPYRIDIN-3-YL THIA (DI) AZOLE DERIVATES FOR USE IN THE TREATMENT OF CELL PROLIFERATION AND APOPTOSIS RELATED DISEASES AMGEN INC. (US) 2004-07-22 WO claimed
US-12636368-B2 Ionizable lipids for nucleic acid delivery GLOBAL LIFE SCIENCES SOLUTIONS CANADA ULC (CA) 2026-05-26 US disclosed
US-4094957-A CARBON DIOXIDE EXXON RESEARCH & ENGINEERING CO. (US) 1978-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12636368-B2 Ionizable lipids for nucleic acid delivery NSUN2, NSUN3, RNMT ALDH1A1 1643/4885SMN1; SMN2 546/4885KMT2A 1599/4885
US-20090221581-A1 Methods of treating pain CDK5, CAMKK2, CDK3 ALDH1A1 2348/4885SMN1; SMN2 935/4885KMT2A 722/4885
US-20130029971-A1 CXCR3 RECEPTOR ANTAGONISTS CXCR3, CXCR1, CXCR2 ALDH1A1 1792/4885SMN1; SMN2 4589/4885KMT2A 3936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.