Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 4/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16789306 | 0.89 | MAPT (0.46) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL6881022 | 0.75 | MAPT (0.50) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL30404833 | 0.75 | MAPT (0.50) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL29408377 | 0.73 | QPCT (0.51) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL1091693 | 0.73 | QPCT (0.51) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL5766962 | 0.73 | MAPT (0.48) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL14511179 | 0.72 | MAPT (0.68) | MAPTKDM4EALDH1A1APEX1RECQL | |
| Hydrochloric Acid SCHEMBL9836827 | 0.72 | QPCT (0.50) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL12445185 | 0.70 | MAPT (0.65) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL8043985 | 0.68 | ATP4A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230247994-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-08-10 | — | — | US | disclosed |
| US-20230247994-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-08-10 | — | — | US | disclosed |
| US-20230247994-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-08-10 | — | — | US | disclosed |
| EP-4175961-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | Bayer Aktiengesellschaft (DE) | 2023-05-10 | — | — | EP | disclosed |
| WO-2022002818-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-01-06 | — | — | WO | disclosed |
| US-6638960-B2 | Use as microbicides, especially fungicides, in crop protection | BAYER AKTIENGESELLSCHAFT (DE) | 2003-10-28 | — | — | US | disclosed |
| EP-0844998-B1 | HALOBENZIMIDAZOLES AND THEIR USE AS MICROBICIDES | BAYER CROPSCIENCE AG (DE) | 2003-04-23 | — | — | EP | disclosed |
| US-20030027842-A1 | Halogenobenzimidazoles | ASSMANN LUTZ (DE) | 2003-02-06 | — | — | US | disclosed |
| US-6387939-B1 | PLANT SAFENING AGNETS; FUNGICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-14 | — | — | US | disclosed |
| US-6268508-B1 | FOR CROP PROTECTION | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-31 | — | — | US | disclosed |
| US-6160001-A | Halobenzimidazoles and their use as microbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | disclosed |
| US-6127547-A | FOR CROP PROTECTION; SUCH AS 2-BROMO-6,6-DIFLUORO(1,3)DIOXOLO(4,5-F)BENZIMIDAZOLE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-03 | — | — | US | disclosed |
| US-6020354-A | FUNGICIDES, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-01 | — | — | US | disclosed |
| EP-0844998-A1 | HALOBENZIMIDAZOLES AND THEIR USE AS MICROBICIDES | BAYER AG (DE) | 1998-06-03 | — | — | EP | disclosed |
| WO-1997006171-A1 | HALOBENZIMIDAZOLES AND THEIR USE AS MICROBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030027842-A1 | Halogenobenzimidazoles | MSR1, MRPS23, CBR1 | MAPT 4367/4885KDM4E 1295/4885ALDH1A1 1161/4885 |
| US-20230247994-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | CHRM1, DDT, H1-0 | MAPT 4309/4885KDM4E 962/4885ALDH1A1 1788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.