Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.49 |
| ▸ | NOS3 | P29474 | 2/20 | 0.49 |
| ▸ | NOS1 | P29475 | 2/20 | 0.49 |
| ▸ | MIF | P14174 | 6/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420416 | 1.00 | NOS2 (0.49) | NOS2NOS3NOS1MIFRECQL | |
| SCHEMBL7420415 | 1.00 | NOS2 (0.49) | NOS2NOS3NOS1MIFRECQL | |
| SCHEMBL6992247 | 1.00 | NOS2 (0.49) | NOS2NOS3NOS1MIFRECQL | |
| SCHEMBL9079735 | 0.84 | MAPT (0.44) | NOS2NOS3NOS1MIFLMNA | |
| SCHEMBL22854418 | 0.84 | NOS3 (0.41) | NOS2NOS3NOS1MIFKMT2A | |
| SCHEMBL9079738 | 0.84 | MAPT (0.44) | NOS2NOS3NOS1MIFLMNA | |
| SCHEMBL29033185 | 0.84 | MAPT (0.44) | NOS2NOS3NOS1MIFLMNA | |
| SCHEMBL13664199 | 0.84 | MAPT (0.44) | NOS2NOS3NOS1MIFLMNA | |
| SCHEMBL8363737 | 0.84 | NOS2 (0.47) | NOS2NOS3NOS1MIFRECQL | |
| SCHEMBL28462081 | 0.84 | NOS2 (0.47) | NOS2NOS3NOS1MIFRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317421-A1 | 2-AMINO-2-ALKYL-5 HEPTENOIC AND HEPTYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | Pharmacia Corporation (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002022562-A1 | 2-AMINO-2-ALKYL-5 HEPTENOIC AND HEPTYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | PHARMACIA CORPORATION (US) | 2002-03-21 | — | — | WO | disclosed |
| US-5554753-A | Catalytic enantioselective synthesis of α-amino acid derivatives by phase-transfer catalysis | INDIANA UNIVERSITY FOUNDATION (US) | 1996-09-10 | — | — | US | disclosed |