Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ARG1 | P05089 | 1/20 | 0.40 |
| ▸ | ARG2 | P78540 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989001 | 1.00 | MEN1 (0.45) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL6988773 | 0.87 | ODC1 (0.42) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL6987908 | 0.86 | NOS1 (0.33) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL2638240 | 0.83 | GGT1 (0.39) | MEN1ALDH1A1CYP1A2KMT2AARG1 | |
| SCHEMBL6475315 | 0.83 | GGT1 (0.39) | MEN1ALDH1A1CYP1A2KMT2AARG1 | |
| SCHEMBL537593 | 0.83 | GGT1 (0.39) | MEN1ALDH1A1CYP1A2KMT2AARG1 | |
| SCHEMBL6190683 | 0.81 | MEN1 (0.44) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| Hydrochloric Acid SCHEMBL6193497 | 0.79 | MEN1 (0.42) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL7071104 | 0.79 | MEN1 (0.36) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL7067315 | 0.79 | MEN1 (0.36) | MEN1ALDH1A1CYP1A2THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317421-A1 | 2-AMINO-2-ALKYL-5 HEPTENOIC AND HEPTYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | Pharmacia Corporation (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002022562-A1 | 2-AMINO-2-ALKYL-5 HEPTENOIC AND HEPTYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | PHARMACIA CORPORATION (US) | 2002-03-21 | — | — | WO | disclosed |